49ers star RB Christian McCaffrey to miss game against Jets with calf, Achilles injury

San Francisco 49ers running back Christian McCaffrey will miss the team’s Monday night game against the New York Jets with a calf and Achilles injury.

McCaffrey was listed as inactive a little over an hour before kickoff.

The star running back was limited in practice all week due to the injury. He was listed as questionable on the team’s injury report, but he told the media Friday he was not concerned about being held back for Week 1.

McCaffrey has been dealing with an injury to his calf and Achilles since August. He did not participate in the preseason before returning to practice Tuesday.

McCaffrey, 28, is a key player for the 49ers’ offense. He carried the ball 272 times for a league-leading 1,459 yards last season. He also caught 67 passes for 564 yards. McCaffrey scored 21 touchdowns for San Francisco in 2023, his first full season with the team after arriving via mid-season trade from Carolina in 2022.

Third-year running back Jordan Mason is listed as McCaffrey’s backup on the 49ers’ depth chart. He played in 17 games last season, running for 206 yards on 40 carries.